價(jià)格 | ¥17400 |
包裝 | 1mg |
最小起訂量 | 1mg |
發(fā)貨地 | 上海 |
更新日期 | 2024-12-02 |
中文名稱:RANK/TNFRSF11A, Mouse, 重組蛋白 (His) | 英文名稱:RANK/TNFRSF11A Protein, Mouse, Recombinant (His) |
品牌: TargetMol | 產(chǎn)地: 美國 |
保存條件: store at low temperature | Shipping with blue ice. | 純度規(guī)格: > 99.9% |
產(chǎn)品類別: 抑制劑 | |
貨號(hào): TMPJ-00674 |
名稱 | RANK/TNFRSF11A Protein, Mouse, Recombinant (His) |
描述 | Receptor activator of NF-κB(RANK,TNFRSF11A) belongs to one member of tumor necrosis factor receptor family.It is a receptor for TNFSF11/RANKL/TRANCE/OPGL. This gene encodes a type 1 membrane protein with a 30 amino acids (aa) signal peptide, 184 aa extracellular region , a 20 aa transmembrane domain and a 391 aa cytoplasmic region. Human and murine RANK share 81% aa identity in their extracellular domains. RANK is ubiquitous highly expressed in trabecular bone, thymus, small intestine, lung, brain and kidney, but weakly expressed in spleen and bone marrow. After binding its ligand RANKL, RANK can activate signaling pathways such as NF-κB, JNK, ERK, p38, and Akt/PKB, through TRAF protein phosphorylation. RANK/TNFRSF11A signaling is largely considered to be growth promoting and apoptosis reducing such as the effects observed in osteoclasts. RANK/TNFRSF11A was also found to be involved in the regulation of interactions between T-cells and dendritic cells. |
存儲(chǔ)條件 | store at low temperature | Shipping with blue ice. |
關(guān)鍵字 | CD-265 | CD 265 |
成立日期 | 2013-04-18 (12年) | 注冊資本 | 589.8595萬人民幣 |
員工人數(shù) | 100-500人 | 年?duì)I業(yè)額 | ¥ 1億以上 |
主營行業(yè) | 中間體,天然產(chǎn)物,生物化工,化學(xué)試劑,生物技術(shù)服務(wù) | 經(jīng)營模式 | 貿(mào)易,工廠,試劑,定制,服務(wù) |
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