價格 | ¥13800 | ¥17500 | ¥10600 |
包裝 | 50mg | 100mg | 25mg |
最小起訂量 | 1mg |
發(fā)貨地 | 上海 |
更新日期 | 2024-09-29 |
中文名稱:化合物 Quinoprazine | 英文名稱:Quinoprazine |
CAS:115618-99-0 | 品牌: TargetMol |
產地: 美國 | 保存條件: Shipping with blue ice. |
產品類別: 抑制劑 | |
貨號: T61651 |
名稱 | Quinoprazine |
描述 | Quinoprazine, a powerful inhibitor of Vaccinia virus DNA synthesis (IC50 = 10 μM), exhibits notable antimalarial activity against Plasmodium berghei. Additionally, it demonstrates significant antiprion potency, effectively reducing levels of PrPSc [1]-[5]. |
體外活性 | Quinoprazine shows antimalarial action against Plasmodium berghei, the chloroquine-resistant isolate LN-K65 [1]. Quinoprazine blocks Vaccinia Virus infection by inhibiting DNA synthesis [2]. Quinoprazine (IND2118) displays good antiprion potency and inhibits baseline PrP S c with reducing rates of 76% (dividing cells) and 51% (nondividing cells), respectively. Reducing PrP S c levels by >30% is considered to have good antiprion potency [3] [4]. Quinoprazine (IND2118) shows low cytotoxicity with reducing rates of 25% (dividing cells) and 24% (nondividing cells), respectively. Reducing cells <30% is considered to have a safe effect [3] [4]. |
體內活性 | Quinoprazine is a 1-alkyl-4-[4-(heterylamino)phenyl]piperazines derivate, Quinoprazine (0.25 g/kg; i.p.; single dose) suppresses the growth of larvocysts of Echinococcus multilocularis in cotton rats [5]. Quinoprazine (0.2-0.5 g/kg; p.o.; single dose) acts against the adult Hymenolepis nana. Exptl. and cures infected mice radically [5]. |
存儲條件 | Shipping with blue ice. |
成立日期 | 2013-04-18 (12年) | 注冊資本 | 589.8595萬人民幣 |
員工人數 | 100-500人 | 年營業(yè)額 | ¥ 1億以上 |
主營行業(yè) | 中間體,天然產物,生物化工,化學試劑,生物技術服務 | 經營模式 | 貿易,工廠,試劑,定制,服務 |
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