Human CEACAM-1 / CD66a Protein, His Tag
分子別名(Synonym)
CEACAM1,CD66a,BGP,BGP1,BGPI
表達區(qū)間及表達系統(tǒng)(Source)
Human CEACAM-1, His Tag (CE1-H5220) is expressed from human 293 cells (HEK293). It contains AA Gln 35 - Gly 428 (Accession # AAH14473).
Predicted N-terminus: Gln 35
蛋白結構(Molecular Characterization)
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 44.1 kDa. The protein migrates as 57-100 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to different glycosylation.
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>92% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
癌胚抗原相關細胞粘附分子1(CEACAM1)也稱為膽汁糖蛋白1(BGP1),CD66a,屬于免疫球蛋白超家族或CEA家族。CEACAM1/CD66a含有三個Ig樣C2型(免疫球蛋白樣)結構域和一個Ig樣V型(免疫蛋白樣)的結構域。CEACAM1/CD66a被描述為一種通過親同和異親方式介導細胞粘附的粘附分子,并在白細胞、上皮細胞和內(nèi)皮細胞上檢測到。研究表明,CEACAM1/BGP-1在多種細胞過程中發(fā)揮作用,包括組織分化、血管生成、凋亡、轉移,以及調(diào)節(jié)先天性和適應性免疫反應。
關鍵字: CEACAM1;CEACAM1蛋白;CEACAM1重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領域提供關鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。