Human CD9 Full Length Protein (VLP)
分子別名（Synonym）
CD9,MIC3,TSPAN29,GIG2,MRP1,BTCC1,DRAP27,5H9
表達區(qū)間及表達系統(tǒng)（Source）
Human CD9 Full Length Protein (VLP) (CD9-H52P3) is expressed from human 293 cells (HEK293). It contains AA Pro 2 - Val 228 (Accession # P21926).
Predicted N-terminus: Met
蛋白結(jié)構(gòu)（Molecular Characterization）
Virus-like particles(VLPs) are formed by self-assembly of envelop/capsid proteins from viruses. Membrane Proteins can be constituted in-situ with VLPs produced from HEK293 cell cultures. These VLPs concentrate conformationally intact membrane proteins directly on the cell surface and produce soluble, high-concentration proteins perfect for immunization and antibody screening.
The VLPs provide the display of properly folded membrane proteins in their native cellular membrane in a compact size of 100~300 nm diameter (similar to the size of most viruses) making it optimal targets for dendritic cells in vivo and surface attachment for phage display.
制劑（Formulation）
The VLPs are highly immunogenic, so the immunization strategy should be optimized (antigen dose, regimen and adjuvant).
Supplied as 0.2 μm filtered solution in PBS, Arginine, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
運輸（Shipping）
This product is supplied and shipped with dry ice, please inquire the shipping cost.
存儲（Storage）
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
The product MUST be stored at -70°C or lower upon receipt;
-70°C for 12 months under sterile conditions.
背景（Background）
CD9抗原也被稱為tetraspanin-29（TSPAN29）、5H9抗原、白細胞抗原MIC3（MIC3）、運動相關(guān)蛋白，是一種多通道膜蛋白，屬于tetraspanin（TM4SF）家族或跨膜4超家族。CD9是一種已知與整合素和其他跨膜4超家族蛋白復(fù)合的細胞表面糖蛋白。TSPAN29存在于外泌體的表面。MIC3參與血小板活化和聚集，調(diào)節(jié)偏執(zhí)連接的形成，還參與細胞粘附、細胞運動和腫瘤轉(zhuǎn)移。CD9抗原似乎也是哺乳動物受精過程中卵子-精子融合的關(guān)鍵部分。
關(guān)鍵字： CD9;CD9蛋白;CD9重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group（股票代碼：301080）是成立于2010年的跨國生物科技公司，是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務(wù)遍布全球，橫跨亞洲、北美洲、歐洲，在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務(wù)客戶超6000家，與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。