Mouse PLGF / PGF Protein, His Tag
分子別名(Synonym)
PGF,PLGF,PlGF,PGFL,SHGC-10760
表達區(qū)間及表達系統(tǒng)(Source)
Mouse PLGF, His Tag (PGF-M52H0) is expressed from human 293 cells (HEK293). It contains AA Val 19 - Pro 158 (Accession # P49764-1).
Predicted N-terminus: Val 19
蛋白結構(Molecular Characterization)
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This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 17.8 kDa. The protein migrates as 27-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in 100 mM HAC, pH2.5 with trehalose as protectant.
Contact us for customized product form or formulation.
重構方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
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背景(Background)
胎盤生長因子(PGF)也稱為血管內(nèi)皮生長因子相關蛋白PLGF和PlGF2,是VEGF(血管內(nèi)皮生長因素)亞家族的成員,是血管生成和血管生成的關鍵分子,特別是在胚胎發(fā)育過程中。妊娠期PGF的主要來源是胎盤滋養(yǎng)層。PGF也在許多其他組織中表達,包括絨毛滋養(yǎng)層。PGF在血管生成和內(nèi)皮細胞生長中具有活性,刺激其增殖和遷移。PlGF2以肝素依賴的方式結合NRP1/神經(jīng)白素-1和NRP2/神經(jīng)白蛋白-2。還促進細胞腫瘤生長。
關鍵字: PLGF;PLGF蛋白;PGF重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領域提供關鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。