Product Name:BMAP-18
CAS No.:1245798-31-5
Synonyms:抗菌肽BMAP-18
Catalog No.:218P965
Brand:HongTide(上海鴻肽生物)
Description:BMAP-18 是一種有生物活性的多肽,是由18個氨基酸組成的多肽,BMAP-18 是抗菌肽 BMAP-27 的截短形式。牛骨髓抗菌肽-27 (BMAP-27) 屬于肽家族 Cathelicidin,對金黃色葡萄球菌、乳房鏈球菌和大腸桿菌具有快速殺菌活性。 BMAP-27 對人紅細胞和中性粒細胞具有細胞毒性,盡管其濃度高于殺菌濃度。與親本 BMAP-27 相比,BMAP-18 顯示出更高的細胞選擇性,因為它降低了溶血活性并保留了抗菌活性。
BMAP-18 is a biologically active peptide composed of 18 amino acids, and is a truncated form of the antimicrobial peptide BMAP-27. Bovine bone marrow-derived antimicrobial peptide-27 (BMAP-27) belongs to the peptide family Cathelicidin and has rapid bactericidal activity against Staphylococcus aureus, Streptococcus pyogenes, and Escherichia coli. BMAP-27 has cytotoxicity towards human red blood cells and neutrophils, although its concentration is higher than the bactericidal concentration. Compared to its parent BMAP-27, BMAP-18 exhibits higher cell selectivity as it reduces hemolytic activity while retaining antibacterial activity.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | GRFKRFRKKFKKLFKKLS |
Sequence(3-letter code) | H-Gly-Arg-Phe-Lys-Arg-Phe-Arg-Lys-Lys-Phe-Lys-Lys-Leu-Phe-Lys-Lys-Leu-Ser-OH |
Peptide Structure |
|
Molecular Formula | C113H188N34O20 |
Molecular Weight | 2342.92 |
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關鍵字: 1245798-31-5;BMAP-18 ;抗菌肽BMAP-18;多肽;多肽合成;
上海鴻肽生物科技有限公司(簡稱:鴻肽生物)是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術轉讓為主要業(yè) 務科技公司。公司現(xiàn)有產(chǎn)品涵蓋:定制多肽、目錄多肽、氨基酸衍生物、小分子化合物;公司自成立以來,秉持“用質量作船, 以服務為帆,為科研服務”的企業(yè)理念,為國內(nèi)外眾多科研工作者提供了優(yōu)質的服務及產(chǎn)品。