產(chǎn)品名稱              人參皂苷 Compound K

英文名稱              Ginsenoside Compound K

植物拉丁名           Panax ginseng C.A. Meyer

科                         五加科

屬                         人參屬

使用部位              根

介紹

人參皂苷（Ginsenoside）是人參及其同屬植物(三七、西洋參等)的主要藥理活性成份，目前已分離出40余種人參皂苷單體。人參皂苷CK屬二醇型皂苷，它在天然人參中的含量極低，但它是其它含量較高人參皂苷Rb1和Rb2等在人體腸道內(nèi)的主要降解產(chǎn)物和最終吸收形式，具有很高的生物活性。

性狀

本品為棕黃色粉末。

可供規(guī)格

1. 1.5%HPLC，適用于特殊及癌癥病患的食品
2. 0.15%HPLC，適用于一般食品

人參皂苷CK的優(yōu)勢(shì)

1.“天然前藥”理論已經(jīng)證實(shí)人參皂苷CK是人參皂苷活性作用的實(shí)體，現(xiàn)有研究表明其抗腫瘤和增強(qiáng)免疫活性是所有人參皂苷中最強(qiáng)的；

2. 人參皂苷CK在所有人參皂苷中最適宜作為抗腫瘤藥用開發(fā)。人參皂苷CK具有良好的水溶液性，而人參皂苷Rg3、Rh1、Rh2水溶性極差。對(duì)惡性腫瘤患者而言，一旦進(jìn)入常規(guī)治療，消化系統(tǒng)功能基本完全喪失，對(duì)口服制劑吸收水平相當(dāng)有限，人參皂苷CK可以憑其良好水溶性制成注射液直接發(fā)揮作用；

3.人參皂苷CK介入具體抗腫瘤藥物治療方案，有助于建立高效的腫瘤治療模式，挖掘現(xiàn)有治療手段和藥物的治療潛力?，F(xiàn)有研究表明，人參皂苷CK確實(shí)對(duì)某些一線抗腫瘤藥物具有良好減毒增效作用

藥理功能

1.抗腫瘤：人參皂苷CK抗腫瘤機(jī)制主要表現(xiàn)以下幾點(diǎn)：A抑制腫瘤細(xì)胞增殖；B促進(jìn)腫瘤細(xì)胞凋亡；C抑制腫瘤細(xì)胞侵入和轉(zhuǎn)移；D提高化療藥物對(duì)腫瘤細(xì)胞的敏感性，減輕其對(duì)正常細(xì)胞的毒副作用

2. 抗糖尿病，調(diào)節(jié)血糖

3. 免疫調(diào)節(jié)

4. 抗過敏、發(fā)炎

5. 抗高血壓

6. 皮膚保濕

應(yīng)用領(lǐng)域

醫(yī)藥原料 、保健品、食品和飲料 、化妝品

Product Name:  Ginsenoside Compound K

Latin Name in Botany:  Panax ginseng C.A. Meyer

Family: Araliaceae

Genus: Panax

Used Part: Root

Introduction:

Ginsenoside is the main pharmacological active ingredient of panax ginseng and its the same family plants (Panax notoginseng, American ginseng, etc.).  It has been separated more than 40 kinds of ginseng saponin monomer. Ginsenoside CK belongs to diol-type saponins, which is very low in natural ginseng. But it is the main degradation products and the final absorptional form of other high content ginsenosides, like ginsenoside Rb1 and Rb2, ect. Ginsenoside CK has a high biological activity.

Character: Brown yellow powder

Available specifications:

1,  1.5% HPLC, apply to special foods and cancer patients

2,  0.15% HPLC, apply to general food

The advantages of Ginsenoside CK:

1. "Natural prodrug" theory has been confirmed Ginsenoside CK is the entity of Ginsenosides active role. The existing research shows that the anti-tumor activity and enhance immune of Ginsenoside CK is the strongest of all ginsenosides;

2 Ginsenoside CK ginsenosides is the most suitable to use as anti-tumor development in all ginsenosides. It has a good solution, while ginsenoside Rg3, Rh1, Rh2 are in poor water solubility. For cancer patients, once into the conventional treatment, digestive function was completely lost. Preparations for oral absorption level is very limited. But ginsenoside CK can be made into injection, with its good water solubility, to play a direct role.?

3 Ginsenoside CK, intervening specific antineoplastic treatment programs, is help to build efficient cancer treatment modalities, to explore the existing treatments and therapeutic potential. The existing studies have shown that ginsenosides CK indeed has a good synergistic effect attenuation for some first-line anticancer drugs.

Pharmacological functions:

1 anti-tumor:

Following is the main points of Ginsenoside CK anti-tumor mechanism:

A inhibition of tumor cell proliferation;

B to promote tumor cell apoptosis;

C inhibition of tumor cell invasion and metastasis;

D to improve chemotherapy sensitivity of tumor cells, reducing its impact on normal cells side effects

2 anti-diabetic, regulate blood sugar

3 immunomodulatory

4 anti-allergic, anti-inflammatory

5 anti-hypertensive

6 Skin Moisturizer

Applications: Pharmaceutical raw materials, Health products, Food and Beverages, Cosmetics