Monkeypox virus (strain Zaire-96-I-16) A35R Protein, His Tag
分子別名(Synonym)
A35R
表達區(qū)間及表達系統(tǒng)(Source)
Monkeypox virus (strain Zaire-96-I-16) A35R , His Tag (A3R-M52H3) is expressed from human 293 cells (HEK293). It contains AA Arg 58 - Thr 181 (Accession # Q8V4U4).
Predicted N-terminus: Arg 58
蛋白結(jié)構(gòu)(Molecular Characterization)
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 15.5 kDa. The protein migrates as 15 kDa and 17 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
猴痘是由猴痘病毒引起的一種罕見的人畜共患病,猴痘病毒已成為最嚴重的正痘病毒,由復雜的雙鏈DNA組成。這些病例大多發(fā)生在中非和西非。猴痘的發(fā)病機制是病毒從呼吸道粘膜侵入人體,在淋巴細胞中繁殖,并進入血液,產(chǎn)生短暫的性病毒血癥。病毒在細胞中繁殖后,細胞可以侵入血液并傳播到全身皮膚,引起病變。EV表面的包膜糖蛋白A35R被預測會影響病毒顆粒的細胞間擴散。
關(guān)鍵字: A35R;A35R蛋白;猴痘病毒;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。