Human CD30 / TNFRSF8 Protein, His Tag
分子別名(Synonym)
TNFRSF8,CD30,D1S166E,Ki-1
表達區(qū)間及表達系統(tǒng)(Source)
Human CD30, His Tag (CD0-H52H5) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Lys 379 (Accession # NP_001234.2).
Predicted N-terminus: Phe 19
蛋白結構(Molecular Characterization)

This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 40.4 kDa. The protein migrates as 53-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
內毒素(Endotoxin)
Less than 0.1 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景(Background)
人CD30也稱為TNFRSF8,是腫瘤壞死因子受體家族的細胞膜蛋白和腫瘤標志物。TNFRSF-8由活化的T細胞和B細胞表達,但不由靜息的T細胞或B細胞表達。此外,CD30與CD15一起在經典霍奇金淋巴瘤細胞上表達。CD30是TNFSF8/CD30L的受體。CD30可以與TRAF2和TRAF5相互作用,介導導致NF-kappa-B激活的信號轉導。TNFRSF8可能在調節(jié)細胞生長和活化淋巴母細胞的轉化中發(fā)揮作用。TNFRSF8是凋亡的積極調節(jié)因子,也被證明可以限制自身反應性CD8效應T細胞的增殖潛力,保護身體免受自身免疫。
關鍵字: TNFRSF8;CD30蛋白;CD30重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產業(yè)領域提供關鍵生物試劑產品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設有辦公室、研發(fā)中心及生產基地。目前累計服務客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。