VSIG3產(chǎn)品信息
別稱:VSIG3,IgSF11,CXADRL1,Bt-IgSF,CT119
物種:Human
屬性:Protein
標(biāo)記:Biotin-labeled/Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in Tris with Glycine, Arginine and NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
VSIG3分子背景
VSIG3,也稱為IGSF11、BT-IgSF和CLMP,是一種優(yōu)先在大腦中表達(dá)的親同粘附分子。VSIG3的功能是通過同源相互作用刺激細(xì)胞生長。在臨床上,VSIG3已被報道為胃腸道和肝細(xì)胞癌癌癥免疫療法的新靶點(diǎn)。此外,VSIG-3也是B7家族成員VISTA/PD-1H的配體,并通過一種新的VSIG-3/VISTA途徑抑制人類T細(xì)胞功能。VSIG-3/VISTA共抑制通路可能為治療人類癌癥和自身免疫性疾病提供新的策略。
關(guān)鍵字: VSIG3;VSIG3蛋白;VSIG3重組蛋白;ACRO;百普賽斯;
百普賽斯集團(tuán)ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團(tuán)業(yè)務(wù)遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設(shè)有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務(wù)客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團(tuán)旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學(xué)等。