Human IL-1RL1 / ST2 Protein, His Tag
分子別名(Synonym)
IL1RL1,DER4,FIT-1,IL33R,ST2,ST2L,ST2V,T1
表達區(qū)間及表達系統(tǒng)(Source)
Human IL-1RL1, His Tag (IL1-H5229) is expressed from human 293 cells (HEK293). It contains AA Lys 19 - Phe 328 (Accession # Q01638-2).
Predicted N-terminus: Lys 19
蛋白結(jié)構(gòu)(Molecular Characterization)
This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 36.9 kDa. The protein migrates as 48-60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>95% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.
背景(Background)
白介素1受體樣1(IL1RL1)也稱為ST2、DER4、FIT-1、IL33R、ST2L、ST2V,屬于白介素-1受體家族。IL1RL1包含三個Ig樣C2型(免疫球蛋白樣)結(jié)構(gòu)域和一個TIR結(jié)構(gòu)域。IL1RL1是白細胞介素-33(IL-33)的受體,其刺激激活MYD88、IRAK1、IRAK4和TRAF6,隨后磷酸化MAPK3/ERK1和/或MAPK1/ERK2、MAPK14和MAPK8。IL1RL1可能參與輔助T細胞功能。IL1RL1可以與MYD88、IRAK1、IRAK4和TRAF6相互作用。
關(guān)鍵字: IL-1RL1;IL-1RL1蛋白;IL1RL1重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產(chǎn)業(yè)領(lǐng)域提供關(guān)鍵生物試劑產(chǎn)品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設有辦公室、研發(fā)中心及生產(chǎn)基地。目前累計服務客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關(guān)系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。