USAG-1產品信息
英文名稱:Sclerostin domain-containing protein 1
中文名稱:含有硬化蛋白結構域的蛋白質-1
靶點別稱:USAG-1
物種:Human
屬性:Protein
標記:Unconjugated
內毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in 51 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.
Contact us for customized product form or formulation.
重構方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

USAG-1分子背景
USAG1(子宮致敏相關基因1),也稱為SOSTDC1(含硬骨素結構域1),Ectodin,是一種分泌蛋白,其N端糖基化,C端半胱氨酸結結構域。這種C-末端半胱氨酸結結構域存在于多種生長因子中,包括TGFβ、NGF、PDGF、vWF、NDP和粘蛋白-2,并參與二聚化、受體結合和信號轉導。SOSTDC1在細胞增殖、分化和凋亡的幾個生物過程中負調控BMP信號傳導(如牙形態(tài)發(fā)生、胚胎植入子宮內膜和骨折愈合)。此外,SOSTDC1還可能通過調節(jié)Wnt途徑參與癌癥的發(fā)展過程。

關鍵字: USAG-1;USAG-1蛋白;USAG-1重組蛋白;ACRO;百普賽斯;
百普賽斯集團ACROBiosystems Group(股票代碼:301080)是成立于2010年的跨國生物科技公司,是為全球生物醫(yī)藥、健康產業(yè)領域提供關鍵生物試劑產品及解決方案的行業(yè)平臺型基石企業(yè)。2021年在創(chuàng)業(yè)板上市。百普賽斯集團業(yè)務遍布全球,橫跨亞洲、北美洲、歐洲,在中國、美國、瑞士等12個城市設有辦公室、研發(fā)中心及生產基地。目前累計服務客戶超6000家,與全球Top 20醫(yī)藥企業(yè)均建立了長期、穩(wěn)定的合作伙伴關系。集團旗下?lián)碛衅放艫CROBiosystems百普賽斯、bioSeedin柏思薈、Condense Capital墾拓資本和ACRODiagnostics百斯醫(yī)學等。