英文名稱:
Methotrexate
CAS號(hào):
59-05-2
分子式:
C20H22N8O5
分子量:
454.45
EINECS號(hào):
200-413-8
MDL No.:
MFCD00064370
熔點(diǎn)
195°C
比旋光度
+17~+24°(D/20℃)(c=1,Na2CO3 soln.)(calculated on the dehydrous basis)
沸點(diǎn)
561.26°C (rough estimate)
密度
1.4080 (rough estimate)
折射率
1.6910 (estimate)
閃點(diǎn)
11℃
儲(chǔ)存條件
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
溶解度
H2O: insoluble
形態(tài)
powder
酸度系數(shù)(pKa)
pKa 3.04/4.99(H2O,t =25,I=0.0025) (Uncertain)
水溶解性
Insoluble. <0.1 g/100 mL at 19 oC
敏感性
Light Sensitive & Hygroscopic
Merck
14,5985
BRN
70669
BCS Class
3
穩(wěn)定性
Stable, but light sensitive and hygroscopic. Incompatible with strong acids, strong oxidizing agents. Store at -15C or below.
InChIKey
FBOZXECLQNJBKD-ZDUSSCGKSA-N
危險(xiǎn)性符號(hào)(GHS)
GHS06,GHS08
警示詞
Danger
危險(xiǎn)性描述
H301-H315-H319-H341-H360D
防范說(shuō)明
P201-P301+P310+P330-P302+P352-P305+P351+P338
危險(xiǎn)品標(biāo)志
T,F
危險(xiǎn)類別碼
61-25-36/38-46-39/23/24/25-23/24/25-11
安全說(shuō)明
53-26-36/37-45-36/37/39-36-16
危險(xiǎn)品運(yùn)輸編號(hào)
UN 2811 6.1/PG 3
WGK Germany
RTECS號(hào)
MA1225000
F
3-8-10
TSCA
Yes
危險(xiǎn)等級(jí)
6.1(b)
包裝類別
III
海關(guān)編碼
29335995
毒性
LD50 oral in rat: 135mg/kg
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