鹽酸伊伐布雷定中文同義詞鹽酸伊伐布雷啶;鹽酸伊伐布雷定IVABRADINE(研發(fā)中);鹽酸伊伐布雷定及中間體;鹽酸伊伐布雷定(依法布雷定);依伐布雷定鹽酸鹽;鹽酸依伐布雷定;鹽酸伊伐布雷;鹽酸伊伐布雷定/鹽酸依法布雷定英文名稱Ivabradinehydrochloride英文同義詞IvabradineHCl;Ivabradinehydrochloride;3-[3-[[(8S)-3,4-Dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-onehydrochloride;Ivabradinehydrochloride,>=99%;IVABRADINEHYDROCHLORIDE-OTHERCOMPOUNDSCONTAININGANUNFUSEDPYRAZOLERING(WHETHERORNOTHYDROGENATED)INTHESTRUCTUR;Ivabradinehydrochloride,98%,aIfinhibitor;3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-oneHydrochloride;CorlentorCAS號148849-67-6分子式C27H37ClN2O5分子量505.05EINECS號638-798-3相關(guān)類別小分子抑制劑，天然產(chǎn)物;醫(yī)藥原料藥;醫(yī)藥原料;醫(yī)藥中間體;原料藥;小分子抑制劑;神經(jīng)信號;細(xì)胞生物學(xué)試劑;心臟;藥物雜質(zhì)及中間體;原料;醫(yī)藥、農(nóng)藥及染料中間體;Intermediates&FineChemicals;Pharmaceuticals;API;ChiralReagents;Heterocycles;CardiovascularAPIs;Inhibitors;醫(yī)藥化工類;雜質(zhì)對照品;化學(xué)試劑;臨床檢測標(biāo)準(zhǔn)物質(zhì)Mol文件148849-67-6.mol結(jié)構(gòu)式鹽酸伊伐布雷定性質(zhì)熔點(diǎn)193-196?C比旋光度58921+7.8°;36521+27.8°(c=1%inDMSO)儲存條件2-8°C溶解度在水中的溶解度為≥5mg/mL（加熱）形態(tài)粉末顏色白色至米色旋光性(opticalactivity)[α]/D+5to+9°,c=1inDMSOMerck14,5247InChIKeyHLUKNZUABFFNQS-ZMBIFBSDSA-NSMILESC([C@H]1CC2=CC(OC)=C(OC)C=C12)N(C)CCCN1CCC2=CC(OC)=C(OC)C=C2CC1=O.Cl|&1:1,r|CAS數(shù)據(jù)庫148849-67-6(CASDataBaseReference)鹽酸伊伐布雷定用途與合成方法用途鹽酸伊伐布雷定是首個選擇性和特異性調(diào)節(jié)心率抑制劑,對竇房結(jié)有選擇性作用而對心臟內(nèi)傳導(dǎo)、心肌收縮或心室復(fù)極化無作用。