鹽酸伊伐布雷定中文同義詞鹽酸伊伐布雷啶;鹽酸伊伐布雷定IVABRADINE(研發(fā)中);鹽酸伊伐布雷定及中間體;鹽酸伊伐布雷定(依法布雷定);依伐布雷定鹽酸鹽;鹽酸依伐布雷定;鹽酸伊伐布雷;鹽酸伊伐布雷定/鹽酸依法布雷定英文名稱Ivabradinehydrochloride英文同義詞IvabradineHCl;Ivabradinehydrochloride;3-[3-[[(8S)-3,4-Dimethoxy-8-bicyclo[4.2.0]octa-1,3,5-trienyl]methyl-methylamino]propyl]-7,8-dimethoxy-2,5-dihydro-1H-3-benzazepin-4-onehydrochloride;Ivabradinehydrochloride,>=99%;IVABRADINEHYDROCHLORIDE-OTHERCOMPOUNDSCONTAININGANUNFUSEDPYRAZOLERING(WHETHERORNOTHYDROGENATED)INTHESTRUCTUR;Ivabradinehydrochloride,98%,aIfinhibitor;3-[3-[[[(7S)-3,4-Dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl]methylamino]propyl]-1,3,4,5-tetrahydro-7,8-dimethoxy-2H-3-benzazepin-2-oneHydrochloride;CorlentorCAS號(hào)148849-67-6分子式C27H37ClN2O5分子量505.05EINECS號(hào)638-798-3相關(guān)類別小分子抑制劑，天然產(chǎn)物;醫(yī)藥原料藥;醫(yī)藥原料;醫(yī)藥中間體;原料藥;小分子抑制劑;神經(jīng)信號(hào);細(xì)胞生物學(xué)試劑;心臟;藥物雜質(zhì)及中間體;原料;醫(yī)藥、農(nóng)藥及染料中間體;Intermediates&FineChemicals;Pharmaceuticals;API;ChiralReagents;Heterocycles;CardiovascularAPIs;Inhibitors;醫(yī)藥化工類;雜質(zhì)對(duì)照品;化學(xué)試劑;臨床檢測(cè)標(biāo)準(zhǔn)物質(zhì)Mol文件148849-67-6.mol結(jié)構(gòu)式鹽酸伊伐布雷定性質(zhì)熔點(diǎn)193-196?C比旋光度58921+7.8°;36521+27.8°(c=1%inDMSO)儲(chǔ)存條件2-8°C溶解度在水中的溶解度為≥5mg/mL（加熱）形態(tài)粉末顏色白色至米色旋光性(opticalactivity)[α]/D+5to+9°,c=1inDMSOMerck14,5247InChIKeyHLUKNZUABFFNQS-ZMBIFBSDSA-NSMILESC([C@H]1CC2=CC(OC)=C(OC)C=C12)N(C)CCCN1CCC2=CC(OC)=C(OC)C=C2CC1=O.Cl|&1:1,r|CAS數(shù)據(jù)庫(kù)148849-67-6(CASDataBaseReference)鹽酸伊伐布雷定用途與合成方法用途鹽酸伊伐布雷定是首個(gè)選擇性和特異性調(diào)節(jié)心率抑制劑,對(duì)竇房結(jié)有選擇性作用而對(duì)心臟內(nèi)傳導(dǎo)、心肌收縮或心室復(fù)極化無(wú)作用。