Product Name：Difopein
CAS No.：396834-58-5
Synonyms：特異性競(jìng)爭(zhēng)性抑制劑多肽Difopein (TFA)
Catalog No.：218P589
Brand：HongTide（上海鴻肽生物）
Description：Difopein (TFA) 是 14-3-3 protein (一種高度保守的真核調(diào)節(jié)分子) 的特異性競(jìng)爭(zhēng)性抑制劑多肽，序列中含有62個(gè)氨基酸，可阻止 14-3-3 與靶蛋白結(jié)合的能力，并抑制 14-3-3/配體的相互作用。Difopein (TFA) 誘導(dǎo)細(xì)胞凋亡 (apoptosis) 并增強(qiáng)順鉑殺死細(xì)胞的能力。
Difopein (TFA) is a specific competitive inhibitor peptide of 14-3-3 protein, a highly conserved eukaryotic regulatory molecule. The sequence contains 62 amino acids, which can block the ability of 14-3-3 to bind to target proteins and inhibit the interaction between 14-3-3/ligands. Difopein (TFA) induces apoptosis and enhances the ability of cisplatin to kill cells.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | SADGAPHCVPRDLSWLDLEANMCLPGAAGLDSADGAPHCVPRDLSWLDLEANMCLPGAAGLE |
Sequence(3-letter code) | H-Ser-Ala-Asp-Gly-Ala-Pro-His-Cys-Val-Pro-Arg-Asp-Leu-Ser-Trp-Leu-Asp-Leu-Glu-Ala-Asn-Met-Cys-Leu-Pro-Gly-Ala-Ala-Gly-Leu-Asp-Ser-Ala-Asp-Gly-Ala-Pro-His-Cys-Val-Pro-Arg-Asp-Leu-Ser-Trp-Leu-Asp-Leu-Glu-Ala-Asn-Met-Cys-Leu-Pro-Gly-Ala-Ala-Gly-Leu-Glu-OH |
Peptide Structure | 
|
Molecular Formula | C273H424N76O89S6 |
Molecular Weight | 6387.19 |
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上海鴻肽生物科技有限公司
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關(guān)鍵字： Difopein ;396834-58-5;特異性競(jìng)爭(zhēng)性抑制劑多肽Difopein ;多肽;多肽合成;
上海鴻肽生物科技有限公司（簡(jiǎn)稱：鴻肽生物）是一家以多肽以及多肽上下游產(chǎn)品研發(fā)、生產(chǎn)、銷售以及技術(shù)轉(zhuǎn)讓為主要業(yè) 務(wù)科技公司。公司現(xiàn)有產(chǎn)品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來(lái)，秉持“用質(zhì)量作船， 以服務(wù)為帆，為科研服務(wù)”的企業(yè)理念，為國(guó)內(nèi)外眾多科研工作者提供了優(yōu)質(zhì)的服務(wù)及產(chǎn)品。