LIGHT產(chǎn)品信息
英文名稱(chēng):Tumor necrosis factor superfamily member 14
中文名稱(chēng):腫瘤壞死因子超家族成員14
靶點(diǎn)別稱(chēng):CD258 antigen,CD258,HVEM-L,LIGHT,LTg,TNFSF14,TR2,HVEML
物種:Human / Mouse / Cynomolgus
屬性:Protein / Kits / Cell
標(biāo)記:Unconjugated
內(nèi)毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
純度(Purity)
>90% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制劑(Formulation)
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
重構(gòu)方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存儲(chǔ)(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
1. -20°C to -70°C for 12 months in lyophilized state;
2. -70°C for 3 months under sterile conditions after reconstitution.
LIGHT分子背景
腫瘤壞死因子配體超家族成員14(LIGHT)是一種腫瘤壞死因子(TNF)超家族配體,通過(guò)皰疹病毒進(jìn)入介體(HVEM)和淋巴毒素β受體(LTbetaR)發(fā)出信號(hào)來(lái)調(diào)節(jié)T細(xì)胞免疫反應(yīng)。LIGHT已成為影響CTL介導(dǎo)的腫瘤排斥、同種異體排斥和移植物抗宿主病的T細(xì)胞共刺激信號(hào)的有力發(fā)起者。LIGHT的組成性表達(dá)導(dǎo)致組織破壞和自身免疫樣疾病綜合征。
LIGHT用戶(hù)評(píng)價(jià)
關(guān)鍵字: LIGHT;LIGHT蛋白;CD258;CD258蛋白;LIGHT抗原;
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