Product Description:
Product name: Carfilzomib
Synonyms: Carfilzomib;N-{(2S)-2-[(Morpholin-4-ylacetyl)aMino]-4-phenylbutanoyl}-L-leucyl-N-{(2S)-4-Methyl-1-[(2R)-2-Methyloxiran-2-yl]-1-oxopentan-2-yl}-L-phenylalaninaMide;CarfilzoMib salt;CarfilzoMib/PR 171;PR-171 (CarfilzoMib);(alphaS)-alpha-[(4-Morpholinylacetyl)amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyloxiranyl]carbonyl]butyl]-L-phenylalaninamide;CarfilzoMib, Free Base, >99%;(S)-4-Methyl-N-((S)-1-((S)-4-Methyl-1-((R)-2- Methyloxiran-2-yl)-1 -oxopentan-2-ylaMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
CAS: 868540-17-4
MF: C40H57N5O7
MW: 719.91
Appearance: White crystal powder
Purity: 98%min
Function: Anti-tumor,Antineoplastic
Type: Pharmaceutical Intermediates,Syntheses Material Intermediates.
Package: 25kg/drum or according to customers' requirements
Storage: Store in cool & dry place, keep away from strong light and heat
Shelf life: 2 years when properly stored
What is Carfilzomib?
Carfilzomib (CFZ) is a tetrapeptide epoxyketone and a selective proteasome inhibitor. It is an analog of epoxomicin.
Discovery and early development
Carfilzomib was discovered and advanced to multiple Phase 1 and 2 clinical trials, including a pivotal Phase 2 clinical trial designed to seek accelerated approval. Clinical trials for carfilzomib continue under Onyx Pharmaceuticals, which acquired Proteolix in 2009. In January 2011, the U. S. FDA granted carfilzomib fast-track status, allowing Onyx to initiate a rolling submission of its new drug application for carfilzomib.
Anti-tumour series:
Bortezomib CAS No.:179324-69-7
N-(2-Pyrazinylcarbonyl)-L-phenylalanine CAS No.:114457-94-2
(1R)-(s)-pinanediol 1-ammonium trifluoroacetate-3-methylbutane-1-boronate CAS No.:179324-87-9
(1S,2S,3R,5S)-2,3-Pinanediol CAS No.:18680-27-8
Isobutaneboronic Acid CAS No.:84110-40-7
(2S)-2-Amino-4-methyl-1-[(2R)-2-methyloxiranyl]-1-pentanone trifluoroacetate CAS No.: 247068-85-5
(alphaS)-alpha-[(4-Morpholinylacetyl)amino]benzenebutanoyl-L-leucyl-L-phenylalanine CAS No.: 868540-16-3
Carfilzomib CAS NO.: 868540-17-4
Irinotecan hydrochloride trihydrate CAS NO.:136572-09-3
Irinotecan hydrochloride CAS NO.: 100286-90-6
Irinotecan CAS NO.: 97682-44-5
7-Ethyl-10-hydroxycamptothecin CAS NO.:86639-52-3
1-Chlorocarbonyl-4-piperidinopiperidine hydrochloride CAS NO.: 143254-82-4
關鍵字: Carfilzomib powder,cas 868540-17-4,anti-tumor intermediates