中文名：Pitavastatin Calcium

英文名：Pitavastatin Calcium

中文別名：匹伐他汀鈣

英文別名：Pitavastatin calcium|147526-32-7|Pitavastatin hemicalcium|Livalo|Itavastatin calcium|NK-104|Flovas|Pitavastatin calcium salt|UNII-IYD54XEG3W|IYD54XEG3W|NK 104 (acid)|Nisvastatin|CCRIS 8652|Calcium (3R,5S,E)-7-(2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl

純度：10mM in DMSO

貨號：P421721

包裝：1ml

Cas號：147526-32-7

存儲溫度：-80℃儲存

產品介紹：

Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Alternate studies show that pitavastatin can suppress oxygen production in endothelial cells by inhibiting NADPH oxidase. In addition, pitavastatin reduces the expression of eNOS mRNA while increasing the NO dependent response stimulated by acetylcholine and the calcium ionophore, A23187. Furthermore, pitavastatin inhibits the up-regulation of conductance calcium-activated potassium channels by lowering cholesterol levels in cells.

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