中文名：海藻糖6,6'-二甲藻酸酯

英文名：Trehalose 6,6′-dimycolate

英文別名：Cord Factors

貨號(hào)：T120976

包裝：1mg、5mg

Cas號(hào)：61512-20-7

存儲(chǔ)溫度：-20°C儲(chǔ)存

產(chǎn)品介紹：

To stimulate mouse bone marrow-derived macrophages, Cord Factor was suspended at a concentration of 0.2mg/ml in hexane. Of the resulting solution 1 or 10μg/well were layered in 96-well tissue culture plates and the solvent completely evaporated. Control wells were layered with solvent without Cord Factor and also incubated at 37°C. To this layer of Cord Factor, bone marrow-derived macrophages were added in 100μl of medium and incubated at 37°C for 24 hours before activation e.g. TNF-α production was measured in the supernatant. In vivo pulmonary granuloma formation in mice can be induced by 10μg Cord Factor per mouse applied i.v. in a water/oil/water emulsion.A glycolipid that induces macrophages to release inflammatory cytokines independent of TLR2 or TLR4

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