中文名：LatanoprostAcid,拉坦前列素酸
英文名：LatanoprostAcid
英文別名：Latanoprost acid|41639-83-2|Phxa 85|Phxa-85|CHEBI:63925|Latanprost Free Acid|EJ85341990|PHXA85|(5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoic acid|(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenyl
純度：≥98%
貨號：L133844
包裝：100mg、25mg
Cas號：41639-83-2
存儲溫度：-20°C儲存
產(chǎn)品介紹：
Latanoprost (free acid) is a metabolite of Latanoprost, an F-series prostaglandin (PG) analog which has been approved for use as an ocular hypotensive drμg. Latanoprost is an isopropyl ester, a prodrμg form which is converted to latanoprost (free acid) by endogenous esterase enzymes. The free acid form is 200 times more potent than latanoprost as an FP receptor ligand for the human recombinant FP receptor. Latanoprost is the isopropyl ester of a PGF2α analog containing an aromatic group (17-phenyl) in the ω-chain. Lat-FA is the corresponding carboxylic acid of this analog. Lat-FA is a potent FP receptor agonist with an EC50 of 3.6 nM for human FP receptors, which is twice the potency of PGF2α. Therefore making Latanoprost (free acid) is an activator of PGF2αR.An F-series prostaglandin (PG) analog.
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關(guān)鍵字： Latanoprost acid;41639-83-2;Phxa 85;Phxa-85
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