中文名:7,8-二羥基黃酮水合物
英文名:7,8-Dihydroxyflavone Hydrate
英文別名:7,8-dihydroxyflavone|38183-03-8|7,8-dihydroxy-2-phenyl-4H-chromen-4-one|7,8-DHF|7,8-Dihydroxyflavone hydrate|4H-1-Benzopyran-4-one, 7,8-dihydroxy-2-phenyl-|7,8-Dihydroxy-flavone|7,8-Dihydroxy-2-phenyl-chromen-4-one|7,8-dihydroxy-2-phenylchromen-4-one|7,8-
純度:≥98.0%(HPLC)
貨號(hào):D137213
包裝:1g、5g、25g
Cas號(hào):38183-03-8
存儲(chǔ)溫度:2-8°C儲(chǔ)存,充氬
產(chǎn)品介紹:
7,8-Dihydroxyflavone hydrate is a tyrosine kinase receptor B (TrkB) agonist that binds to the extracellular domain of the receptor with a Kd value of 320 nM. It also inhibits glutamate-triggered apoptosis in hippocampal neurons in vitro.7,8-Dihydroxyflavone (7,8-DHF), a selective tyrosine kinase receptor B (neurotrophic factor/tropomyosin-receptor-kinase B; TrkB) agonist, may be used to help identify and differentiate the physiological effects and cell signaling pathways mediated by TrkB activation, such as those involving neuroprotection, memory, vasorelaxation and hypertension. 7,8-Dihydroxyflavone may be used to study its effects on scopolamine induced Alzheimer-like pathologic dysfunction.
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關(guān)鍵字: 7,8-dihydroxyflavone;38183-03-8;7,8-dihydroxy-2-phenyl-4H-chromen-4-one;7,8-DHF
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