中文名：靛玉紅

英文名：Indirubin

中文別名：靛玉紅|靛紅

英文別名：Indirubin|479-41-4|Indigo Red|Couroupitine B|Indigopurpurin|906748-38-7|(Z)-[2,3'-biindolinylidene]-2',3-dione|[2,3'-Biindolinylidene]-2',3-dione|Isoindirubin|Isoindirubine|Isoindogotin|397242-72-7|Indirubin [MI]|NSC 105327|NSC-105327|(E)-[2,3'-biindoliny

純度：95%

貨號：I111268

包裝：50mg、10mg、250mg

Cas號：479-41-4

存儲溫度：2-8°C儲存

產(chǎn)品介紹：

Indirubin, also known as isoindigotin, is an inhibitor of cyclin-dependent kinases (CDK1/cyclin B (IC50 = 10μM), CDK2/cyclin A (IC50 = 2.2μM), CDK2/cyclin E (IC50 = 7.5μM), CDK4/cyclin D1 (IC50 = 12μM), CDK5/p35 (IC50 = 5.5μM)) and of GSK-3β (IC50 = 600nM). Studies investigating functional isoindigos show that they have the ability to disrupt cell growth and proliferation. The compound is a potent aryl hydrocarbon receptor ligand and is found in human urine and fetal bovine serum. Synthesized isoindigo-based oligothiophenes are used to study heterojunction solar cells. Shown to inhibit allergic contact dermatitis by regulating T helper mediated immune system in a DNCB-induced model. An inhibitor of GSK-3β and cyclin-dependent kinases.

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