中文名：2,4＇-二溴苯乙酮
英文名：2,4'-Dibromoacetophenone
中文別名：4-溴苯甲酰甲基溴|4'-溴苯甲酰甲基溴
英文別名：2,4'-Dibromoacetophenone|99-73-0|2-Bromo-1-(4-bromophenyl)ethanone|p-Bromophenacyl bromide|4-Bromophenacyl bromide|Ethanone, 2-bromo-1-(4-bromophenyl)-|2-bromo-1-(4-bromophenyl)-ethanone|2-bromo-1-(4-bromophenyl)ethan-1-one|4'-Bromophenacyl bromide|132309
純度：98%
貨號：D113568
包裝：100g、25g、5g
Cas號：99-73-0
存儲溫度：2-8°C儲存,避光
產(chǎn)品介紹：
GSK-3β Inhibitor VII is a phenyl α-bromomethyl ketone compound which acts as a cell-permeable, and non-ATP competitive inhibitor of glycogen synthase kinases (GSK-3&beta); (IC = 0.5 μM). This compound acts as an alkylating agent that is selective towards GSK-3β and does not affect PKA activity even at concentrations as high as 100 μM. Research has shown that glycogen synthase kinases have major roles in Wnt and Hedgehog signaling pathways and regulate the cell-division cycle, stem-cell renewal and differentiation, apoptosis, circadian rhythm, transcription and insulin action. This pertinent biological activity makes GSK inhibitors very useful research molecules.A cell-permeable, and non-ATP competitive inhibitor of GSK-3β
應(yīng)用：
在 SnCl2 或 SmI3 存在的情況下與醛發(fā)生縮合反應(yīng)以生成 α,β-不飽和酮。還用于羧酸的酯化反應(yīng)。
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關(guān)鍵字： 4-溴苯甲酰甲基溴;4'-溴苯甲酰甲基溴;2,4'-Dibromoacetophenone;99-73-0
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