別名
Amino sulfonyl fluoride alkyne,Probe building block
應(yīng)用
3-Amino-5-ethynylbenzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its amine linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
其他說明
Technology Spotlight: Trifunctional Probe Building BlocksChemoselective Preparation of Clickable Aryl Sulfonyl Fluoride Monomers: A Toolbox of Highly Functionalized Intermediates for Chemical Biology Probe Synthesis
Sigma-Aldrich西格瑪奧德里奇(上海)貿(mào)易有限公司
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