Rabbit Anti-phospho-STAT6 (Tyr641) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-STAT6 (Tyr641)
IR:Immunogen Range:RG(p-Y)V
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6778
Swiss Prot:P42226
Source:KLH conjugated Synthesised phosphopeptide derived from human STAT6 around the phosphorylation site of Tyr641:RG(p-Y)V
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X (L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Also known as: signal transducers and activators of transduction 6; D12S1644; IL 4 STAT; IL4 STAT; Interleukin 4 Induced; Interleukin 4 Induced Transcription Factor IL4 STAT; Signal Transducer And Activator Of Transcription 6 Interleukin 4 Induced; Signal Transducer And Activator Of Transcription 6 Nirs Variant 1; STAT 6; STAT interleukin4 induced; STAT6B; STAT6C; Transcription factor IL 4 STAT.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Horse
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用!
關(guān)鍵字: phospho-STAT6 (Tyr64;STAT6 (phospho Y641);p-STAT6 (phospho Y64;D12S1644 IL 4 STAT; IL4 STAT;STAT6B;STAT6C;Transcription factor;
上海滬震實(shí)業(yè)有限公司是一家集研發(fā)、生產(chǎn)和銷售于一體的生命科學(xué)實(shí)驗(yàn)室產(chǎn)品生物科技企業(yè)。主營(yíng)產(chǎn)品:試劑盒,ELISA試劑盒,抗體,重組蛋白,血清,胎牛血清,細(xì)胞,原代細(xì)胞 細(xì)胞培養(yǎng)試劑,常用生化試劑。