Rabbit Anti-ZO-1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ZO-1
IR:Immunogen Range:
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7082
Swiss Prot:Q07157
Source:KLH conjugated synthetic peptide derived from human ZO-1:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Background:This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family of proteins, and acts as a tight junction adaptor protein that also regulates adherens junctions. Tight junctions regulate the movement of ions and macromolecules between endothelial and epithelial cells. The multidomain structure of this scaffold protein, including a postsynaptic density 95/disc-large/zona occludens (PDZ) domain, a Src homology (SH3) domain, a guanylate kinase (GuK) domain and unique (U) motifs all help to co-ordinate binding of transmembrane proteins, cytosolic proteins, and F-actin, which are required for tight junction function. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2017]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:200)
ICC(1:200)
Cross Reactive Species:Human
Mouse
Rat
僅供科研使用。不能用于人和動物治療等其它臨床診斷用!
關鍵字: ZO-1;Tight junction prote;TJP1;Tight junction prote; Zona occludens prot;Zonula occludens pro;胞質緊密粘連蛋白1/閉鎖小帶蛋白1抗體;ZO1_HUMAN;
上海滬震實業(yè)有限公司是一家集研發(fā)、生產和銷售于一體的生命科學實驗室產品生物科技企業(yè)。主營產品:試劑盒,ELISA試劑盒,抗體,重組蛋白,血清,胎牛血清,細胞,原代細胞 細胞培養(yǎng)試劑,常用生化試劑。