Rabbit Anti-HLA-DR Monoclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:HLA-DR
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:3122
Swiss Prot:P01903
Source:Recombinant human HLA-DR between 150-250 amino acids:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1, DRB3, DRB4 and DRB5. [provided by RefSeq]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:50-200)
ICC(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： HLA-DR;DRB1;DRB4;HLA DR1B;HLA DR3B;HLA DRA;HLA DRB5;DRA_HUMAN;
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