Rabbit Anti-NQO1 Monoclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:NQO1
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:1728
Swiss Prot:P15559
Source:KLH conjugated synthetic peptide derived from human NQO1:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq].Size:
50ul
Concentration:1mg/ml
Applications:WB(1:1000-3000)
IP(1:20-100)
Flow-Cyt(1:50)
ICC(1:100-500)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用!
關(guān)鍵字: NQO1;Azoreductase;DHQU;DIA4;NMORI;NQO 1;QR1;NQO1_HUMAN;
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