Rabbit Anti-ACACA Monoclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ACACA
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:32
Swiss Prot:Q13085
Source:KLH conjugated synthetic peptide derived from human Acetyl CoA Carboxylase 1(ACC1):
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].Size:
50ul
Concentration:1mg/ml
Applications:WB(1:500-1000)
IHC-P(1:50-200)
IHC-F(1:50-200)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： ACACA;eIF4E(S209); Acetyl-CoA carboxyl;ACC1;Acetyl-Coenzyme A;ACC-alpha;ACAC;ACACA_HUMAN;
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