Mouse Anti-CEA Monoclonal Antibody
DATASHEET
Host:Mouse
Target Protein:CEA
IR:Immunogen Range:41-140/702
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:1048
Swiss Prot:P06731
Source:KLH conjugated synthetic peptide derived from human CEA/CD66e/CEACAM5:41-140/702
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family. It consists of seven CEACAM (CEACAM 1, CEACAM 3-CEACAM 8) and 11 pregnancy-specific glyco-protein (PSG 1-PSG 11) members. The CEA family proteins belong to the immunoglobulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/ CEACAM 5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker. The function of CEACAM family members varies widely: they function as cell adhesion molecules, tumor suppressors, regulators of lymphocyte and dendritic cell activation, receptors of Neisseria species and other bacteria.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： CEA;CD66e;CD66e antigen;CEACAM5;DKFZp781M2392;Meconium antigen 100;Carcinoembryonic ant;CEAM5_HUMAN;
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