Rabbit Anti-HABP4 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:HABP4
IR:Immunogen Range:41-140/413
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:22927
Swiss Prot:Q5JVS0
Source:KLH conjugated synthetic peptide derived from human HABP4:41-140/413
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The intracellular hyaluronan-binding protein 4 is a cytoplasmic and nuclear protein that is phosphorylated on serine and threonine residues. HABP4 is expressed as a protein of 413 amino acids and is phosphorylated by phorbol 12-myristate 13-acetate (PMA)-activated PKC isoforms at Thr-354 and Thr-375. HABP4 interacts with hyaluron, the adaptor protein RACK1, the transcription factor MEF2C and the chromatin remodeling factor CHD3, suggesting that it may be involved in the regulation of transcription. However, its actual function has yet to be elucidated. HABP4 is highly expressed in brain, heart, and kidney and is moderately expressed in skeletal muscle. Also, HABP4 is expressed in a variety of tumor cell lines and in activated, but not resting, leukocytes.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Sheep
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用!
關(guān)鍵字: HABP4;IHABP-4;Intracellular ;hyaluronan-binding ;protein 4; Ki-1/57 intracellul;透明質(zhì)酸結(jié)合蛋白4抗體;HABP4_HUMAN;
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