Rabbit Anti-P2RX7 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:P2RX7
IR:Immunogen Range:115-160/595
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5027
Swiss Prot:Q99572
Source:KLH conjugated synthetic peptide derived from human P2RX7:115-160/595
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Horse
Rabbit
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： P2RX7;ATP receptor;P2X purinoceptor 7;P2X7;P2Z receptor;Purinergic receptor;purinergic receptor ;P2RX7_HUMAN;
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