Rabbit Anti-CDKN2B/p15 INK4b Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CDKN2B/p15 INK4b
IR:Immunogen Range:65-138/138
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1030
Swiss Prot:P42772
Source:KLH conjugated synthetic peptide derived from human CDKN2B:65-138/138
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:p15 INK4b / MTS 2 (Mitotic Inhibitor / Suppressor Protein) is a specific inhibitor of cdk 4 / cdk 6 and is periodically expressed during the cell cycle. Reportedly, p15 INK4b expression is induced approximately 30 fold in human keratinocytes by treatment with TGF beta, suggesting that p15 INK4b may act as an effector of TGF beta mediated cell cycle arrest. p15 INK4b is mapped to chromosome 9p21, a region of frequent loss in a wide variety of cancers.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
Rabbit
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用!
關(guān)鍵字: CDKN2B/p15 INK4b;CDK inhibitory prote;CDK4B Inhibitor;CDKN2B;Cyclin dependent kin;MTS2;TP15;p15INK4B;
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