Rabbit Anti-NEK2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:NEK2
IR:Immunogen Range:1-100/445
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:4751
Swiss Prot:P51955
Source:KLH conjugated synthetic peptide derived from human NEK2:1-100/445
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Protein kinase that is involved in mitotic regulation. Integral component of the mitotic spindle-assembly checkpoint which is necessary for proper chromosome segregation during metaphase-anaphase transition. Required for association of MAD2L1 to kinetochore. Phosphorylates SGOL1. May have a role at the G2-M transition. May also play a role in meiosis. Isoform 1 but not isoform 2 appears to play a role in centrosome splitting. Isoform 1 phosphorylates and activates NEK11 in G1/S-arrested cells. Isoform 2, which is not present in the nucleolus, does not.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
Rabbit
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： NEK2;Serine/threonine-pro;HSPK 21;Never in mitosis A-r;NimA-related protein;NimA-like protein ki;中心體相關蛋白激酶Nek2抗體;NEK2_HUMAN;
上海滬震實業(yè)有限公司是一家集研發(fā)、生產和銷售于一體的生命科學實驗室產品生物科技企業(yè)。主營產品：試劑盒，ELISA試劑盒，抗體，重組蛋白，血清，胎牛血清，細胞，原代細胞 細胞培養(yǎng)試劑，常用生化試劑。