Rabbit  Anti-phospho-PRKCQ (Thr538) Polyclonal Antibody
DATASHEET

Host:Rabbit

Target Protein:phospho-PRKCQ (Thr538)

IR:Immunogen Range:TN(p-T)FC

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:5588

Swiss Prot:Q04759

Source:KLH conjugated Synthesised phosphopeptide derived from human PRKCQ around the phosphorylation site of Thr538:TN(p-T)FC 

Purification:affinity purified by Protein A

Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

Background:Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008]

Size:50ul

Concentration:1mg/ml

Applications:WB(1:500-2000)
ELISA(1:5000-10000)

Cross Reactive Species:Human
Mouse
Rat
Dog

僅供科研使用。不能用于人和動物治療等其它臨床診斷用！