Rabbit Anti-Phospho-SHIP1 (Tyr1020) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-SHIP1 (Tyr1020)
IR:Immunogen Range:PL(p-Y)GS
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:65038
Swiss Prot:P97573
Source:KLH conjugated Synthesised phosphopeptide derived from rat SHIP1 around the phosphorylation site of Tyr1020:PL(p-Y)GS
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:SHIP1 is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and contains an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation in response to multiple cytokine and B and T cell receptor activation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. Overall the protein functions as a negative regulator of myeliod cell proliferation and survival.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： Phospho-SHIP1 (Tyr10;SHIP (phospho Y1020);p-SHIP (phospho Y102;SHIP1 (Phospho Tyr10; SHIP1 (Phospho-Tyr1;INPP5D;INPP5D protein;MGC142142;
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