Rabbit Anti-p53BP1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:p53BP1
IR:Immunogen Range:501-600/1977
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:7158
Swiss Prot:Q12888
Source:KLH conjugated synthetic peptide derived from human p53BP1/53BP1:501-600/1977
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, p53 binding protein 1 (53BP1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, it is phosphorylated and relocalizes to the presumptive sites of damage, specifically, double strand breaks. This also suggests a role in DNA repair, maintaining genomic stability.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Rabbit
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： p53BP1;FLJ41424;MGC138366;p202;p53 binding protein ;TP53 BP1;tumor protein 53-bin;TP53B_HUMAN;
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