Rabbit Anti-ANT1+ANT2+ANT3+ANT4 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ANT1+ANT2+ANT3+ANT4
IR:Immunogen Range:51-150/298
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:291
Swiss Prot:P12235
Source:KLH conjugated synthetic peptide derived from human ANT1/2/3/4:51-150/298
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Adenine nucleotide translocator (ANT) and the voltage-dependent anion-selective channel proteins 1 and 2 (VDAC1 and VDAC2) are components of the permeability transition pore complex (PTPC) of the mitochondrial inner and outer membranes, respectively. Formation of PTPCs, the subsequent dissipation of mitochondrial inner membrane potential and release of cytochrome c through the outer mitochondrial membrane are critical events in the early stages of apoptosis. Bax, a proapoptotic protein, has been shown to act upon ANT to induce the dissipation of mitochondrial inner membrane potential. ANT1 has a role in the maintenance of mitochondrial DNA by catalyzing the exchange of ADP and ATP across the mitochondrial inner membrane.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Horse
Rabbit
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： ANT1+ANT2+ANT3+ANT4;ATP carrier protein ;ADP ATP carrier prot; ADP/ATP translocase;ANT;ANT1;ADT4_HUMAN;ADT1_HUMAN;
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