Rabbit Anti-ACP5 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:ACP5
IR:Immunogen Range:101-200/325
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:54
Swiss Prot:P13686
Source:KLH conjugated synthetic peptide derived from human TRAP/Tartrate Resistant Acid Phosphatase:101-200/325
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Tartrate-resistant acid phosphatase is an iron containing glycoprotein that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. TRAP is the most basic of the acid phosphatases and is the only form not inhibited by L+-tartrate. TRAP is a relatively minor lysosomal enzyme which may be activated in certain pathologies such as Hodgkin’s disease and B- and T-cell leukemias. Receptor activator of NFκB ligand (RANKL) plays an essential role in osteoclast differentiation and activation by increasing the expression of protease osteoclast markers such as TRAP. TRAP has collagenolytic activity and plays a major role in ligament degradation.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Horse
Rabbit
僅供科研使用。不能用于人和動物治療等其它臨床診斷用!
關(guān)鍵字: ACP5;T5ap;Tartrate resistant a;Tartrate resistant a;TR AP;TrATPase;Type 5 acid phosphat;PPA5_HUMAN;
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