Rabbit Anti-phospho-ERK5 ( Ser731+Thr733) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-ERK5 ( Ser731+Thr733)
IR:Immunogen Range:VF(p-S)G(p-T)PK
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5598
Swiss Prot:Q13164
Source:KLH conjugated Synthesised phosphopeptide derived from human ERK5 around the phosphorylation site of Ser731+Thr733:VF(p-S)G(p-T)PK
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Rabbit
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： phospho-ERK5 ( Ser73;ERK5 (phospho Ser731;Big MAP kinase 1;BMK 1;BMK 1 kinase;BMK1;ERK4;OTTHUMP00000065907;
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