Rabbit Anti-Phospho-PAK6 (Ser560) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-PAK6 (Ser560)
IR:Immunogen Range:RK(p-S)LV
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:56924
Swiss Prot:Q9NQU5
Source:KLH conjugated Synthesised phosphopeptide derived from human PAK6 around the phosphorylation site of Ser560:RK(p-S)LV
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
ICC(1:100)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
Sheep
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關鍵字： Phospho-PAK6 (Ser560;CDKN1A activated kin;Serine/threonine-pro;p21 activated protei;PAK5;C 2.7.1.37;PAK-5;PAK6_HUMAN;
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