Rabbit Anti-phospho-MEK2 (Thr394) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:phospho-MEK2 (Thr394)
IR:Immunogen Range:PG(p-T)PT
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:5605
Swiss Prot:P36507
Source:KLH conjugated Synthesised phosphopeptide derived from human MEK2 around the phosphorylation site of Thr394:PG(p-T)PT
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： phospho-MEK2 (Thr394;MEK2 (phospho T394);p-MEK2 (phospho T394;MEK2(Phospho-Thr394);map2k2; MAPK / ERK kinase 2;MKK2;MP2K2_HUMAN;
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