Rabbit Anti-MDC1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:MDC1
IR:Immunogen Range:31-130/2089
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:9656
Swiss Prot:Q14676
Source:KLH conjugated synthetic peptide derived from human NFBD1:31-130/2089
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. [provided by RefSeq].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Cow
Horse
僅供科研使用。不能用于人和動(dòng)物治療等其它臨床診斷用！
關(guān)鍵字： MDC1;NFBD1;Nuclear factor with ;DKFZp781A0122;KIAA0170;MGC166888;MDC 1;MDC1_HUMAN;
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