Product Name：LSKL
CAS No.：283609-79-0
Synonyms：Inhibitor of Thrombospondin TSP-1；抑制劑多肽LSKL
Catalog No.：209P03
Brand：HongTide（上海鴻肽生物）
Description：LSKL是由4個氨基酸組成的抑制劑多肽，是一種與潛伏期相關肽衍生的多肽，可抑制TGF-β的血小板反應蛋白（TSP-1）活化，并防止肝損傷、纖維化；同時，LSKL可以輕松穿越血腦屏障，減輕腦積水；LSKL可通過拮抗TSP-1來成功減弱TGF-β-Smad信號的激活，但不能降低TSP-1的蛋白表達；LSKL還能促進肝切除術后肝細胞增殖。
LSKL is an inhibitor peptide composed of four amino acids, which is derived from latency related peptides and can inhibit TGF- β Activation of platelet reactive protein (TSP-1) and prevention of liver injury and fibrosis; At the same time, LSKL can easily cross the Blood–brain barrier to reduce Hydrocephalus; LSKL can successfully weaken TGF by antagonizing TSP-1- β- The activation of Smad signal cannot reduce the protein expression of TSP-1; LSKL can also promote hepatocyte proliferation after Hepatectomy.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | LSKL-NH2 |
Sequence(3-letter code) | H-Leu-Ser-Lys-Leu-NH2 |
Peptide Structure | 
|
Molecular Formula | C21H42N6O5 |
Molecular Weight | 458.59 |
訂購聯系方式：
上海鴻肽生物科技有限公司
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關鍵字： LSKL ;283609-79-0;抑制劑多肽LSKL;多肽;多肽合成;
上海鴻肽生物科技有限公司（簡稱：鴻肽生物）是一家以多肽以及多肽上下游產品研發(fā)、生產、銷售以及技術轉讓為主要業(yè) 務科技公司。公司現有產品涵蓋：定制多肽、目錄多肽、氨基酸衍生物、小分子化合物；公司自成立以來，秉持“用質量作船， 以服務為帆，為科研服務”的企業(yè)理念，為國內外眾多科研工作者提供了優(yōu)質的服務及產品。