Rabbit Anti-Ribonuclease 3/ECP Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Ribonuclease 3/ECP
IR:Immunogen Range:45-160/160
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6037
Swiss Prot:P12724
Source:KLH conjugated synthetic peptide derived from human Ribonuclease 3:45-160/160
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:ECP is a 160 amino acid potent cytotoxic secretory protein that belongs to the pancreatic ribonuclease family. ECP localizes to the granule matrix of the eosinophil and is involved in the immune response system. ECP is a cytotoxin, neurotoxin and helminthotoxin that is secreted by activated human eosinophils. ECP exhibits anti-parasitic, antibacterial and ribonucleolytic activities. It has been suggested that ECP induces the neurotoxic effect known as the Gordon phenomenon, a syndrome manifested by ataxia, muscular rigidity, paralysis, and tremor that may lead to death. ECP is considered a marker of eosinophilic inflammation and high levels have been found in cases of active asthma and other allergic diseases
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
ICC(1:100-500)
Cross Reactive Species:Human
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僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： Ribonuclease 3/ECP;eosinophil cationic ;EAR;Ear11;Ear4;EAR5;MGC143624;ECP_HUMAN;
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