Rabbit Anti-CLEC 4E Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CLEC 4E
IR:Immunogen Range:51-150/219
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:26253
Swiss Prot:Q9ULY5
Source:KLH conjugated synthetic peptide derived from human CLECSF9:51-150/219
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(2μg/Test)
IF(1:50-200)
Cross Reactive Species:Human
Mouse
Rat
Cow
Horse
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： CLEC 4E;C type lectin domain;C type lectin superf;CLEC4E Clec4e;CLEC4E ;CLECSF9;MINCLE;CLC4E_HUMAN;
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