Rabbit Anti-CACNA1S Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CACNA1S
IR:Immunogen Range:901-1000/1873
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:779
Swiss Prot:Q13698
Source:KLH conjugated synthetic peptide derived from human CACNA1S:901-1000/1873
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1S gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Rabbit
僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： CACNA1S;L-type Ca++ CP α1S;alpha-1 polypeptide;CACH1;Cach1b;CACN1;CACNA1S;CAC1S_HUMAN;
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