Rabbit Anti-GSTA3 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:GSTA3
IR:Immunogen Range:131-222/222
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2940
Swiss Prot:Q16772
Source:KLH conjugated synthetic peptide derived from human GSTA3:131-222/222
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. Glutathione S-transferase A3 (GSTA3) belongs to the alpha class genes that are located in a cluster mapped to chromosome 6. Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity. However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity. GSTA3 catalyzes the double bond isomerization of precursors for progesterone and testosterone during the biosynthesis of steroid hormones.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Pig
Horse
Rabbit
Sheep
僅供科研使用。不能用于人和動物治療等其它臨床診斷用!
關鍵字: GSTA3;Glutathione S aralky;Glutathione S alkylt;GSTA 3;Glutathione S aryltr;GSTA3 3; Glutathione S trans;GTA3;
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