Rabbit Anti-Frizzled 7 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Frizzled 7
IR:Immunogen Range:501-574/574
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:8324
Swiss Prot:O75084
Source:KLH conjugated synthetic peptide derived from human Frizzled 7:501-574/574
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The Frizzled 7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Frizzled family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. Frizzled 7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. Frizzled 7 expression has been reported in brain, gastrointestinal tract, heart, fetal kidney, fetal lung, placenta, skeletal muscle, and various cancers. ESTs have been isolated from a wide variety of normal and cancer libraries.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(3ug/Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Guinea Pig
本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： Frizzled 7;Frizzled drosophila ;Frizzled homolog 7;Frizzled7 Fz 7;Fz7;FZD 7;FZE3;Frizzled3;
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