Rabbit Anti-thymidine phosphorylase Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:thymidine phosphorylase
IR:Immunogen Range:121-220/482
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1890
Swiss Prot:P19971
Source:KLH conjugated synthetic peptide derived from human Thymidine Phosphorylase:121-220/482
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
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本品僅供科研使用。不能用于人和動物治療等其它臨床診斷用！
關(guān)鍵字： thymidine phosphoryl;phosphoryl;ECGF 1;PDEGF;Endothelial cell gro;MNGIE;PD ECGF;TYPH_HUMAN;
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